![]() Postlicensure safety surveillance for 7-valent pneumococcal conjugate vaccine. Wise RP, Iskander J, Pratt RD, Campbell S, Ball R, et al. Signal identification and evaluation for risk of febrile seizures in children following trivalent inactivated influenza vaccine in the Vaccine Safety Datalink Project, 2010-2011. Tse A, Tseng HF, Greene SK, Vellozzi C, Lee GM VSD Rapid Cycle Analysis Influenza Working Group. Use of PCV-13 and PPSV-23 vaccine among adults aged 65 and older: Recommendations of the ACIP. What are the symptoms of pneumonitis Pneumonitis can cause: Shortness of breath. Tomczyk S, Bennett NM, Stoecker C, Gierke R, Moore MR, Whitney CG, et al. Pneumonitis can be serious or life-threatening and can happen at any time during treatment or even after treatment has ended. Immunogenicity and safety of a 13-valent pneumococcal conjugate vaccine in adults 70 years of age and older previously vaccinated with 23-valent pneumococcal polysaccharide vaccine. Immunogenicity and safety of a 13-valent pneumococcal conjugate vaccine compared to a 23-valent pneumococcal polysaccharide vaccine in pneumococcal vaccine-naive adults. Jackson LA, Gurtman A, van Cleeff M, et al. If you have pneumonia, you’ll probably feel unwell and have symptoms like flu. Rationale and design of CAPITA: A RCT of 13-valent conjugated pneumococcal vaccine efficacy among older adults. Licensure of 13-valent pneumococcal conjugate vaccine for adults aged 50 years and older. Pneumovax 23 is recommended for all adults 65 years of age and older and for those 2 years and older who are at increased risk for pneumococcal disease.Ĭenters for Disease Control and Prevention. It protects against 23 types of pneumococcal bacteria. Pneumovax 23 (PPSV23) : FDA approved this vaccine in 1983.It is also recommended to help prevent pneumococcal disease in individuals 6 through 64 years of age with certain medical conditions that place them at increased risk for pneumococcal disease. It is recommended for routine use among children younger than 5 years of age and adults 65 years of age and older. PCV13 protects against the 13 types of pneumococcal bacteria that cause the most severe illness among children and adults. Pneumococcal vaccines are inactivated, meaning they contain only parts of the bacteria, or they are designed to trick the. PCV13 replaced a previous pneumococcal vaccine, PCV7. Prevnar13 (PCV13) : The Food and Drug Administration (FDA) approved this vaccine in 2010 for use in children and in 2011 for use in adults.There was no evidence of an increased risk of pneumonia.Īcute exacerbation Chronic obstructive pulmonary disease Gastroesophageal reflux disease Pneumonia Proton pump inhibitor.There are two pneumococcal vaccines approved for use in the United States: Severe exacerbation may increase due to uncontrolled GERD but subsequently decrease following PPI treatment. The risk of exacerbation was significantly reduced after PPI treatment compared with the non-treated period. The results were similar in patients with incident COPD. Pneumonia risk was not significantly increased during the PPI treatment. The risk of severe exacerbation increased during the PPI treatment but significantly decreased in the post-treatment period. The risk of moderate exacerbation was significantly lower during the PPI treatment than at baseline. A self-controlled case series analysis was conducted to calculate the risk of moderate and severe exacerbation and pneumonia.Ī total of 104,439 patients with prevalent COPD received PPI treatment for GERD. ![]() Patients aged ≥ 40 years with COPD as a main diagnosis and who received PPI treatment for GERD at least for 14 consecutive days between January 2013 and December 2018 were included in the study. This study used a reimbursement database of the Republic of Korea. This study aimed to evaluate the risks of both exacerbation and pneumonia following PPI treatment for GERD in patients with COPD. However, it remains undetermined whether proton pump inhibitor (PPI) treatment reduces the risk of exacerbation or affects the risk of pneumonia. Gastroesophageal reflux disease (GERD) has been suggested as a risk factor for acute exacerbation of chronic obstructive pulmonary disease (COPD).
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